Horizontal Gaze Palsy: Additional Issues
نویسنده
چکیده
I read with interest the article by Gautam, et al. [1]. I agree that brainstem tuberculoma can cause nuclear gaze palsy and fascinating neuro-ophthalmological findings. However, I think further clarification regarding pathophysiological mechanism of the gaze palsy may be interesting for the readers. Particularly, two points I want to raise are: difficulty in differentiating pathological lesions located in VI nerve nucleus and parapontine reticular formation (PPRF), and less usefulness of vestibule-ocular reflex to differentiate between lesions present in these two anatomical regions.
منابع مشابه
Convergence substitution for paralysed horizontal gaze.
Three patients with paralysed horizontal gaze are presented. Involuntary use of convergence to assist horizontal gaze was noted as a late feature. All patients showed (1) unilateral or bilateral horizontal gaze palsy (two patients had one and a half syndrome, the other had bilateral nuclear sixth nerve palsies), (2) adduction of both eyes on attempted gaze into the paralysed field, (3) miosis w...
متن کاملCongenital horizontal gaze palsy and kyphoscoliosis in two brothers.
In a sibship of 11, two brothers with a congenital complete horizontal gaze palsy developed severe kyphoscoliosis. No-one else in the family has a gaze palsy or comparable skeletal abnormalities. Since the parents are first cousins, an autosomal recessive mode of inheritance seems likely.
متن کاملAbnormalities of horizontal gaze. Clinical, oculographic and magnetic resonance imaging findings. II. Gaze palsy and internuclear ophthalmoplegia.
The site of lesions responsible for horizontal gaze palsy and various types of internuclear ophthalmoplegia (INO) was established by identifying the common areas where the abnormal MRI signals from patients with a given ocular-motor disorder overlapped. Patients with unilateral gaze palsy had lesions in the paramedian area of the pons, including the abducens nucleus, the lateral part of the nuc...
متن کاملIpsilateral stroke in a patient with horizontal gaze palsy with progressive scoliosis and a subcortical infarct.
BACKGROUND AND PURPOSE horizontal gaze palsy with progressive scoliosis (HGPPS) is a rare congenital disorder caused by mutation in the ROBO3 gene. It is characterized by absent horizontal eye movements with progressive scoliosis developing in childhood and adolescence. To our knowledge, both diffusion tensor imaging evaluation in HGPPS patients who present with stroke and truncating stop codon...
متن کاملAn uncommon case of horizontal Gaze Palsy with scoliosis and associated brain-stem anomaly (HGPPS)
HGPPS is a rare congenital disorder resulting from cranial nuclear maldevelopment and characterized by absence of conjugate horizontal eye movements, preservation of vertical gaze & convergence, progressive scoliosis developing in childhood and hypoplasia of dorsomedial brainstem structures associated with sagittal cleft of pons and medulla. We present a 19 years old male, with restriction of e...
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تاریخ انتشار 2015